Luigi D Notarangelo Selected Research

Interferon Regulatory Factor-7 (Interferon Regulatory Factor 7)

10/2020	Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.
4/2015	Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Luigi D Notarangelo Research Topics

Disease

43	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 12/2023 - 02/2005
33	COVID-19 12/2023 - 09/2020
31	Infections 12/2023 - 09/2002
18	Pneumonia (Pneumonitis) 11/2023 - 02/2004
18	Wiskott-Aldrich Syndrome 01/2020 - 07/2005
17	Primary Immunodeficiency Diseases 10/2023 - 01/2002
11	Lymphopenia (Lymphocytopenia) 01/2023 - 07/2010
9	Virus Diseases (Viral Diseases) 11/2023 - 09/2010
8	Autoimmune Diseases (Autoimmune Disease) 10/2023 - 03/2005
8	Inflammation (Inflammations) 12/2022 - 12/2008
7	Neoplasms (Cancer) 10/2023 - 08/2004
7	Thrombocytopenia 1 11/2015 - 10/2003
6	Chronic Granulomatous Disease 01/2024 - 01/2016
6	Autoimmune Polyendocrinopathies (Schmidt Syndrome) 11/2023 - 12/2004
6	Graft vs Host Disease (Graft-Versus-Host Disease) 10/2023 - 04/2014
6	Severe combined immunodeficiency due to adenosine deaminase deficiency 01/2022 - 05/2002
5	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 01/2023 - 12/2005
5	Cytopenia 01/2023 - 09/2015
5	Thrombocytopenia (Thrombopenia) 01/2020 - 03/2002
5	Neutropenia 07/2019 - 06/2007
5	Hyper-IgM Immunodeficiency Syndrome (Hyper-IgM Syndrome) 10/2018 - 07/2003
5	Cartilage-hair hypoplasia 01/2017 - 12/2008
4	Eosinophilia 01/2023 - 12/2008
4	Candidiasis (Moniliasis) 09/2021 - 12/2004
4	Type 1 Hyper-IgM Immunodeficiency Syndrome 11/2018 - 12/2003
4	Reticular dysgenesis 12/2017 - 04/2014
4	Job Syndrome (Hyper-IgE Syndrome) 04/2014 - 12/2008
3	Opportunistic Infections (Opportunistic Infection) 01/2023 - 12/2003
3	Granuloma 01/2023 - 12/2014
3	Human Influenza (Influenza) 11/2022 - 04/2015
3	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 10/2022 - 01/2022
3	COVID-19 related pediatric multisystem inflammatory disease 10/2022 - 01/2022
3	Lymphoma (Lymphomas) 01/2019 - 08/2004
3	Agammaglobulinemia (Hypogammaglobulinemia) 12/2018 - 07/2008
3	X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency) 01/2016 - 01/2008
3	Common Variable Immunodeficiency 05/2015 - 09/2005
3	Sepsis (Septicemia) 01/2015 - 09/2002
3	Bruton type agammaglobulinemia 03/2013 - 03/2004
2	Parasitic Diseases (Parasitic Disease) 02/2024 - 12/2008
2	Down Syndrome (Down's Syndrome) 01/2023 - 11/2022
2	Lymphadenopathy 01/2023 - 01/2019
2	Respiratory Insufficiency (Respiratory Failure) 09/2022 - 11/2008
2	Purine Nucleoside Phosphorylase Deficiency 01/2022 - 07/2014
2	Hypersensitivity (Allergy) 01/2022 - 04/2014
2	type 1 Autoimmune polyendocrinopathy syndrome 01/2021 - 01/2015

Drug/Important Bio-Agent (IBA)

28	AutoantibodiesIBA 11/2023 - 01/2009
26	Proteins (Proteins, Gene)FDA Link 01/2023 - 03/2002
13	AntibodiesIBA 10/2022 - 12/2008
11	InterferonsIBA 12/2023 - 01/2015
10	CytokinesIBA 02/2024 - 11/2006
10	T-Cell Antigen Receptors (T-Cell Receptor)IBA 12/2023 - 08/2014
10	VaccinesIBA 10/2023 - 04/2014
10	AntigensIBA 01/2023 - 03/2005
9	Interferon Type IIBA 12/2023 - 11/2018
8	Immunoglobulin E (IgE)IBA 01/2023 - 12/2008
8	Immunoglobulins (Immunoglobulin)IBA 11/2018 - 07/2008
6	Messenger RNA (mRNA)IBA 12/2023 - 03/2005
6	EnzymesIBA 10/2023 - 05/2002
6	Immunoglobulin G (IgG)IBA 10/2023 - 09/2002
6	Intravenous Immunoglobulins (IVIG)FDA Link 01/2023 - 01/2002
6	Biomarkers (Surrogate Marker)IBA 09/2022 - 01/2021
6	Wiskott-Aldrich Syndrome ProteinIBA 01/2019 - 07/2005
5	SteroidsIBA 01/2024 - 11/2015
5	CD40 Ligand (CD40L)IBA 01/2021 - 02/2004
5	Immunoglobulin A (IgA)IBA 12/2019 - 07/2010
4	AutoantigensIBA 10/2022 - 11/2018
4	Peptides (Polypeptides)IBA 01/2022 - 04/2011
4	Adenosine DeaminaseIBA 01/2022 - 01/2019
3	mRNA VaccinesIBA 12/2023 - 11/2021
3	Oxidoreductases (Dehydrogenase)IBA 12/2023 - 01/2022
3	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2023 - 01/2007
3	Recombinases (Recombinase)IBA 08/2023 - 01/2021
3	DNA Ligases (Ligases, DNA)IBA 01/2023 - 12/2018
3	Antiviral Agents (Antivirals)IBA 01/2023 - 10/2021
3	CalciumIBA 01/2018 - 07/2003
3	Immunoglobulin M (IgM)IBA 07/2010 - 08/2004
2	EpitopesIBA 12/2023 - 01/2022
2	NADP (NADPH)IBA 12/2023 - 01/2022
2	ruxolitinibIBA 12/2022 - 05/2017
2	Transcription Factors (Transcription Factor)IBA 12/2022 - 04/2015
2	COVID-19 VaccinesIBA 11/2022 - 06/2022
2	2- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA 10/2022 - 03/2022
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2022 - 01/2022
2	trichostatin A (A 300)IBA 01/2022 - 01/2021
2	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 01/2022 - 01/2021
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 01/2020
2	Niacinamide (Nicotinamide)FDA LinkGeneric 01/2022 - 01/2021
2	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2022 - 01/2021
2	Busulfan (Busulfex)FDA Link 01/2022 - 01/2020
2	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2018
2	Ligases (Synthetase)IBA 01/2021 - 12/2019
2	purineIBA 01/2021 - 10/2009
2	MitogensIBA 01/2021 - 12/2009

Therapy/Procedure

21	Cell Transplantation 01/2024 - 12/2008
19	Therapeutics 12/2023 - 01/2002
18	Hematopoietic Stem Cell Transplantation 10/2023 - 07/2003
16	Transplantation 01/2023 - 12/2006
3	Stem Cell Transplantation 01/2022 - 12/2006
3	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2020 - 02/2006
3	Drug Therapy (Chemotherapy) 12/2017 - 08/2004